The Download: GLP-1s and eating disorders, self-aware cities, and forever chemicals

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This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Eating disorders are on the rise. GLP-1s could make things worse. GLP-1 weight-loss drugs are one of the biggest biotech breakthroughs of the last decade. But to some clinicians, they can represent something sinister—a potential trigger for eating disorders. A new report suggests the global incidence of anorexia nervosa and bulimia nervosa shot up by 71% between 1990 and 2023. And clinicians are already seeing GLP-1s exacerbate the issue. Here’s how they could make an already growing problem worse. —Jessica Hamzelou This story is from The Checkup, our weekly biotech newsletter. Sign up to receive it in your inbox every Thursday.

这是今日版《下载》（The Download），是我们提供每日科技界动态的平日通讯。饮食失调症正在增加，而 GLP-1 类药物可能会使情况恶化。GLP-1 减肥药是过去十年中最大的生物技术突破之一。但在一些临床医生看来，它们可能代表着某种险恶的东西——即饮食失调的潜在诱因。一份新报告显示，1990 年至 2023 年间，全球神经性厌食症和神经性贪食症的发病率激增了 71%。临床医生已经观察到 GLP-1 类药物正在加剧这一问题。以下是它们如何使一个本已日益严重的问题变得更糟。——Jessica Hamzelou，本文摘自我们的每周生物技术通讯《检查》（The Checkup）。请注册订阅，以便每周四在收件箱中接收。

Love is infrastructure —“Love is Infrastructure” is a short fictional story by Charlie Jane Anders, author of a forthcoming novel titled Good Things Are Coming Your Way. Mainspring and St. Barnabas are two neighboring cities with different personalities. They’ve never particularly liked each other, but that changes when both develop minds of their own, shaped by the votes of their residents. As the cities begin to fall for each other, a third city enters the picture. Turnbull promises Mainspring a more efficient future, but its vision of urban life comes with a troubling price. Read the full short story about self-aware cities, direct democracy, and a steamy romance. This story is from the latest edition of our print magazine. Subscribe now to get every issue as soon as it lands.

爱即基础设施——《爱即基础设施》（Love is Infrastructure）是由查理·简·安德斯（Charlie Jane Anders）创作的一篇短篇小说，她是即将出版的小说《好运即将来临》（Good Things Are Coming Your Way）的作者。主发条城（Mainspring）和圣巴拿巴（St. Barnabas）是两个性格迥异的邻近城市。它们向来不太喜欢对方，但当两者在居民投票的影响下产生自我意识时，情况发生了变化。随着两座城市开始坠入爱河，第三座城市出现了。特恩布尔（Turnbull）向主发条城承诺了一个更高效的未来，但其城市生活的愿景却伴随着令人不安的代价。阅读这篇关于自我意识城市、直接民主和热烈浪漫故事的完整短篇小说。本文摘自我们印刷版杂志的最新一期。立即订阅，即可在每期出版时第一时间收到。

Are we there yet? Cleaning up PFAS Used for decades in everything from nonstick pans to firefighting foams, PFAS, or “forever chemicals,” are linked to increased risks of fertility challenges, developmental delays, cancer, and reduced immune response. Scrubbing PFAS-contaminated soil could eliminate a list of woes for people and planet. The concept is still in its infancy, but we can limit their buildup by pulling the chemicals out of water systems. Find out how close we are to ridding the world of forever chemicals. —Sara Kiley Watson This story is part of “Are we there yet?”, our series that takes stock of six technologies that have long promised to change the world—and scores them on a progress meter. We’re exploring each one in The Download, so stay tuned, and subscribe to read the rest of the stories in our new Impossible issue.

到了吗？清理 PFAS。PFAS 或称“永久化学品”，几十年来被用于从不粘锅到消防泡沫的各种产品中，与生育挑战、发育迟缓、癌症和免疫反应降低的风险增加有关。清除受 PFAS 污染的土壤可以消除人类和地球面临的一系列困扰。这一概念仍处于起步阶段，但我们可以通过从水系统中提取这些化学物质来限制它们的积累。了解我们距离彻底清除世界上的“永久化学品”还有多远。——Sara Kiley Watson，本文是我们“到了吗？”（Are we there yet?）系列的一部分，该系列盘点了六项长期承诺改变世界的科技，并用进度表对它们进行了评分。我们将在《下载》中逐一探讨，敬请关注，并订阅以阅读我们新一期《不可能》（Impossible）特刊中的其余故事。

The must-reads I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology. 1 Binance has suffered the biggest crypto hack in history. The exchange says $6.3 billion in assets were affected. (BBC)+ Analysts blamed the hack on North Korea. (Guardian)+ The Bitcoin stolen will likely never be recovered. (Bloomberg $)+ Binance has suspended all deposits and withdrawals. (NBC News)+ How a pastor’s crypto scheme lost investors millions. (MIT Technology Review)

必读内容：我梳理了互联网，为您找出了今天关于科技的最有趣、最重要、最可怕和最引人入胜的故事。1. 币安（Binance）遭遇了历史上最大的加密货币黑客攻击。该交易所称有 63 亿美元的资产受到影响。（BBC）+ 分析师将此次黑客攻击归咎于朝鲜。（卫报）+ 被盗的比特币可能永远无法追回。（彭博社 $）+ 币安已暂停所有充值和提现。（NBC 新闻）+ 一位牧师的加密货币骗局如何让投资者损失数百万美元。（麻省理工科技评论）

2 Nvidia’s Jensen Huang was targeted by an alleged Chinese spy. The suspect is an executive at a Singapore data center firm. (NYT $)+ US intelligence believes she cultivated ties with Huang. (Guardian)+ Her company was investigated over alleged chip diversion. (CNBC)+ Nvidia says their dealings were “normal.” (Bloomberg $)

2. 英伟达（Nvidia）的黄仁勋成为了一名涉嫌中国间谍的目标。嫌疑人是一家新加坡数据中心公司的高管。（纽约时报 $）+ 美国情报部门认为她与黄仁勋建立了联系。（卫报）+ 她的公司因涉嫌芯片转移而受到调查。（CNBC）+ 英伟达表示他们的往来是“正常的”。（彭博社 $）

3 Alphabet just shed $500 billion in market value. The record loss is due to AI taking a bite out of its search profits. (CNBC)+ Amazon and Intel further a further fall in tech stocks. (Bloomberg $)+ Hyperscalers are making a trillion-dollar gamble. (MIT Technology Review)

3. Alphabet 市值蒸发了 5000 亿美元。这一创纪录的损失是因为人工智能蚕食了其搜索利润。（CNBC）+ 亚马逊和英特尔进一步加剧了科技股的下跌。（彭博社 $）+ 超大规模云服务商正在进行一场万亿美元的赌博。（麻省理工科技评论）

4 The Pentagon suspects freezers at military bases were hacked. The malfunctions spoiled food. (Reuters $)+ They may be linked to similar hacks in French supermarkets. (Gizmodo)

4. 五角大楼怀疑军事基地的冷冻柜遭到黑客攻击。故障导致食物变质。（路透社 $）+ 这些攻击可能与法国超市发生的类似黑客攻击有关。（Gizmodo）

5 The US midterms could reshape the future of American science. A Democratic Congress could curb Trump’s science cuts. (Nature)+ Trump has already dealt big blows to science. (MIT Technology Review)

5. 美国中期选举可能会重塑美国科学的未来。民主党控制的国会可能会遏制特朗普对科学领域的削减。（自然）+ 特朗普已经对科学造成了沉重打击。（麻省理工科技评论）

6 Data centers are set to send US climate pollution skyrocketing. Gas plants could push power-sector emissions up 42% by 2030. (Verge)+ Europe’s data centre workers face dangerous conditions. (Guardian)

6. 数据中心将导致美国气候污染飙升。天然气发电厂可能会使电力行业的排放量在 2030 年前增加 42%。（Verge）+ 欧洲的数据中心工人面临危险的工作环境。（卫报）

7 SpaceX is pulling away from NASA. The company is prioritising Starlink and AI. (Ars Technica)+ But Cape Canaveral is busier than during the space race. (Axios)

7. SpaceX 正在疏远 NASA。该公司优先考虑星链（Starlink）和人工智能。（Ars Technica）+ 但卡纳维拉尔角比太空竞赛时期还要繁忙。（Axios）

8 Battery makers are finding a new market in the US. They’re pivoting from EVs to grid storage. (WSJ $)+ Batteries just broke another record in the US. (MIT Technology Review)

8. 电池制造商正在美国寻找新市场。他们正从电动汽车转向电网储能。（华尔街日报 $）+ 电池在美国刚刚打破了另一项纪录。（麻省理工科技评论）

9 A humanist has received a religious exemption from using AI at work. He argued that using it undermined human flourishing. (Gizmodo)

9. 一位人文主义者获得了在工作中免于使用人工智能的宗教豁免权。他认为使用人工智能损害了人类的繁荣。（Gizmodo）

10 Psychics are fighting back against computerized clairvoyance. Human practitioners say chatbots lack the divine touch. (Guardian)

10. 通灵者正在反击计算机化的千里眼。人类从业者表示聊天机器人缺乏神圣的触感。（卫报）

Quote of the day “Rizz is in more and more demand because it’s something that only people have.” —Steven Strogatz, a mathematics professor at Cornell University, tells Business Insider that personal appeal will become more valuable as AI increasingly takes over intellectual work.

今日名言：“‘魅力’（Rizz）的需求越来越大，因为这是只有人类才拥有的东西。”——康奈尔大学数学教授史蒂文·斯特罗加茨（Steven Strogatz）告诉《商业内幕》（Business Insider），随着人工智能越来越多地接管智力工作，个人魅力将变得更有价值。

One more thing The Bay Area’s animal welfare movement wants to recruit AI. In early February, animal welfare advocates and AI researchers arrived in stocking feet at Mox, a shoes-free coworking space in San Francisco. They gathered to discuss a provocative idea: if artificial general intelligence is on the horizon, could it prevent animal suffering? Some brainstormed using custom agents in advocacy work, while others pitched cultivating meat with AI tools. But the real talk of the event was a flood of funding they expect will soon flow to animal welfare charities, not from individual megadonors, but from AI lab employees. Some attendees also probed an even more controversial idea: AI may develop the capacity to suffer, which could constitute a moral catastrophe. We investigated why their ideas are gaining momentum—and sparking controversy. —Michelle Kim & Grace Huckins

还有一件事：湾区的动物福利运动想要招募人工智能。二月初，动物福利倡导者和人工智能研究人员穿着袜子来到了旧金山的 Mox，这是一个需要脱鞋的联合办公空间。他们聚集在一起讨论一个挑衅性的想法：如果通用人工智能即将到来，它能防止动物受苦吗？一些人集思广益，探讨在倡导工作中使用定制代理，而另一些人则提议利用人工智能工具培育肉类。但活动的真正焦点是他们预计很快会涌向动物福利慈善机构的大量资金，这些资金并非来自个人大额捐赠者，而是来自人工智能实验室的员工。一些与会者还探讨了一个更具争议的想法：人工智能可能会发展出受苦的能力，这可能构成一场道德灾难。我们调查了为什么他们的想法正在获得动力——并引发争议。——Michelle Kim & Grace Huckins

We can still have nice things A place for comfort, fun, and distraction to brighten up your day. Today, it’s a Halloween special. (Got any ideas? Drop me a l

我们依然可以拥有美好的事物：一个为您提供舒适、乐趣和消遣，点亮您一天的地方。今天，这是万圣节特辑。（有什么想法吗？给我发个 l